Significance of Splenic Vein Thrombosis in Chronic Pancreatitis
Splenic vein thrombosis is described by all types of hyper coagulant disorders, whether congenital or acquired. However, in this disease, local intra-abdominal events, with or without hyper coagulable disorders, directly leads to a significant proportion of splenic vein thrombosis. The main causes are pancreatitis and pancreatic cancer due to the close contact between the splenic vein and the pancreas. Pancreatitis is the causative event, and isolated splenic vein thrombosis is found in up to 65% of cases. Splenic vein thrombosis has also been reported after abdominal injury and abdominal surgery. This complicates 11% of all splenectomy procedures, but is common in patients who have had their splenectomy removed for haematological reasons. Therefore, conditions that require splenectomy such as myeloproliferative disorders may be more "coagulated" than the surgery itself. Splenic vein thrombosis has historically been associated with splenectomy for Immune Thrombocytopenic Purpura (ITP). This association is most likely due to the association between ITP and APLS and describes both ITP and splenic vein thrombosis. SVT is a rare symptom of Venous Thromboembolism (VTE). VTE occurs in normal areas, deep vein thrombosis and pulmonary embolism in the lower extremities occur in approximately 70-270 cases with an SVT incidence of at least 1/25. In addition, it has been reported that the incidence of SVT varies widely. This depends on the type of data source, the difference in diagnostic tests, the location, or the type of accidental or symptomatic SVT considered.
Journal of Thrombosis and Circulation is an Open Access and peer reviewed journal that publishes studies related to blood circulation and thrombosis.
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